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Steroid hormone innovation platform
Led by Tianjin Steroid Drug Enterprise Key Laboratory, its steroid hormone innovation platform independently developed a number of key technologies, including three core technologies, namely biological oxidation, biological dehydrogenation and biological degradation, which broken the technical blockade of foreign countries for 30 years, exclusively enjoyed the advantages of domestic process using domestic saponin and sterol as raw materials, and established its international leading position in steroid APIs.
Won the Second Prize of National Science and Technology Progress twice and the Special Prize of Tianjin Science and Technology Progress. Built a new type of pharmaceutical preparation bio-fermentation technology, high-end preparation technology and quality control technical barrier with international advanced level, and realized the industrialization and internationalization of high-end preparation products. Obtained FDA approval for its methylprednisolone sodium succinate for injection, methylprednisolone tablets, prednisone tablets, celecoxib capsules and other varieties, and passed the evaluation of consistency of domestic drugs.
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Innovative platform for inhaled drugs
Led by Tianjin Steroid Drug Enterprise Key Laboratory, its steroid hormone innovation platform independently developed a number of key technologies, including three core technologies, namely biological oxidation, biological dehydrogenation and biological degradation, which broken the technical blockade of foreign countries for 30 years, exclusively enjoyed the advantages of domestic process using domestic saponin and sterol as raw materials, and established its international leading position in steroid APIs.
Won the Second Prize of National Science and Technology Progress twice and the Special Prize of Tianjin Science and Technology Progress. Built a new type of pharmaceutical preparation bio-fermentation technology, high-end preparation technology and quality control technical barrier with international advanced level, and realized the industrialization and internationalization of high-end preparation products. Obtained FDA approval for its methylprednisolone sodium succinate for injection, methylprednisolone tablets, prednisone tablets, celecoxib capsules and other varieties, and passed the evaluation of consistency of domestic drugs.
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Secondary development platform for proprietary Chinese medicine
Relying on the TCM Institute of Tianjin Pharmaceutical Da Ren Tang Group Corporation Limited and led by Tianjin TCM Quality Control Enterprise Key Laboratory, the proprietary Chinese medicine secondary development platform carries out the secondary development research on proprietary Chinese medicine, including expanding indications, improving drug forms, material basis of classic prescriptions, quality control, mechanism of action, evidence-based medicine and pharmacoeconomics. It has established a scientific and reasonable TCM quality evaluation system and evaluation standards, and comprehensively improved the quality control level of the whole industrial chain of proprietary Chinese medicine.
It developed LC-MS/MS method for methodological research on 30 kinds of banned pesticides remaining in various Chinese herbal medicines and decoction pieces; It has established a variety of rapid detection methods for amedicinal materials, and improved the rapid detection methods for varieties such as Suxiao Jiuxin Pills and Shunao Xindi Pills; Through study on the chemical components of traditional Chinese medicine, research on phytochemistry and the material basis of pharmacodynamics, and clarifying the material basis of pharmacodynamics, it has comprehensively improved the technical level in the field of TCM quality control and accelerated the industrialization process of new traditional Chinese medicine.
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